Stage IVb There are distant metastases, with spread to organs within the abdomen and/or disease in the groin lymph nodes . Standard Treatment Metastatic sarcomas are usually treated with chemotherapy . Commonly used drugs include doxorubicin or ifosfamide alone and the combinations of vincristine + actinomycin-D or doxorubicin + cyclophosphamide + DTIC . Five-Year Survival 0 to 5 percent Investigational • Various doses and combinations of chemotherapy drugs are being evaluated. • Mitoxantrone , a drug similar to doxorubicin, is being studied.